Nanoformulated Zoledronic Acid Boosts the Vδ2 T Cell Immunotherapeutic Potential in Colorectal Cancer

Nanoformulated Zoledronic Acid Boosts the Vδ2 T Cell Immunotherapeutic Potential in Colorectal Cancer

Aminobisphosphonates, such as zoledronic acid (ZA), have shown potential in the treatment of different malignancies, including colorectal carcinoma (CRC). Yet, their clinical exploitation is limited by their high bone affinity and modest bioavailability. Here, ZA is encapsulated into the aqueous cor...

Full description

Bibliographic Details
Main Authors: Daniele Di Mascolo, Serena Varesano, Roberto Benelli, Hilaria Mollica, Annalisa Salis, Maria Raffaella Zocchi, Paolo Decuzzi, Alessandro Poggi
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Cancers
Subjects:
vδ2 t cells
zoledronic acid
polymeric nanoconstruct
anti-tumor immunity
colorectal carcinoma
Online Access:https://www.mdpi.com/2072-6694/12/1/104

Internet

https://www.mdpi.com/2072-6694/12/1/104

Similar Items