Expression of Mitochondrial Branched-Chain Aminotransferase and α-Keto-Acid Dehydrogenase in Rat Brain: Implications for Neurotransmitter Metabolism

In the brain, metabolism of the essential branched chain amino acids (BCAAs) leucine, isoleucine and valine, is regulated in part by protein synthesis requirements. Excess BCAAs are catabolized or excreted. The first step in BCAA catabolism is catalyzed by the branched chain aminotransferase (BCAT)...

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Bibliographic Details
Main Authors: Jeffrey Thomas Cole, Andrew J Sweatt, Susan M Hutson
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Neuroanatomy
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnana.2012.00018/full