Cranberry (Vaccinium macrocarpon) peel polyphenol-rich extract attenuates rat liver mitochondria impairments in alcoholic steatohepatitis in vivo and after oxidative treatment in vitro

Cranberry (Vaccinium macrocarpon) peel polyphenol-rich extract attenuates rat liver mitochondria impairments in alcoholic steatohepatitis in vivo and after oxidative treatment in vitro

Alcoholic steatohepatitis is an important medical problem but its effective therapies are still not available. Plant polyphenols are widely used for prevention of toxic liver damages. The aim of the study was to evaluate the hepatoprotective mechanism(s) of a cranberry peel polyphenol-rich extract,...

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Bibliographic Details
Main Authors: Ilya Zavodnik, Vyacheslav Buko, Oxana Lukivskaya, Elena Lapshina, Tatsiana Ilyich, Elena Belonovskaya, Siarhei Kirko, Elena Naruta, Irina Kuzmitskaya, Grazyna Budryn, Dorota Zyzelevicz, Joanna Orach, Agnieszka Zakrzeska, Lyudmila Kiryukhina
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Journal of Functional Foods
Subjects:
Liver
Alcoholic steatohepatitis
Cranberry peel polyphenols
Mitochondrial permeability transition
Mitochondrial ultrastructure
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464619301793

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http://www.sciencedirect.com/science/article/pii/S1756464619301793

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