Oxidative coupling of sp 2 and sp 3 carbon–hydrogen bonds to construct dihydrobenzofurans

Cross-dehydrogenative coupling is finding increasing application in synthesis, but coupling two chemically distinct sites remains a challenge. Here, the authors report an oxidative coupling between sp 2 and sp 3 carbons by sequentially activating the more active aryl site followed by the alkyl posit...

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Bibliographic Details
Main Authors: Jiang-Ling Shi, Ding Wang, Xi-Sha Zhang, Xiao-Lei Li, Yu-Qin Chen, Yu-Xue Li, Zhang-Jie Shi
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00078-6