Toxic effects of different doses of cyclophosphamide on the reproductive parameters of male mice

The cyclophosphamide is used in cancer treatment. The aim of this study was evaluating the effect of different doses of this drug on male mice reproductive parameters. The cyclophosphamide was administered in the doses 100, 150, 200 e 250 mg.kg-1, intraperitoneal route, for six weeks. As a result, i...

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Bibliographic Details
Main Authors: Tatiane Yumi Nakamura Kanno, Lucimara Aparecida Sensiate, Natália Aparecida de Paula, Maria José Sparça Salles
Format: Article
Language:English
Published: Universidade de São Paulo 2009-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000200017