Sperm chromatin-induced ectopic polar body extrusion in mouse eggs after ICSI and delayed egg activation.

Meiotic chromosomes in an oocyte are not only a maternal genome carrier but also provide a positional signal to induce cortical polarization and define asymmetric meiotic division of the oocyte, resulting in polar body extrusion and haploidization of the maternal genome. The meiotic chromosomes play...

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Bibliographic Details
Main Authors: Manqi Deng, Rong Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2746308?pdf=render