Short-Term Esmolol Improves Coronary Artery Remodeling in Spontaneously Hypertensive Rats through Increased Nitric Oxide Bioavailability and Superoxide Dismutase Activity

Short-Term Esmolol Improves Coronary Artery Remodeling in Spontaneously Hypertensive Rats through Increased Nitric Oxide Bioavailability and Superoxide Dismutase Activity

The aim of this study was to assess the effects of short-term esmolol therapy on coronary artery structure and function and plasma oxidative stress in spontaneously hypertensive rats (SHR). For this purpose, 14-month-old male SHR were treated for 48 hours with esmolol (SHR-E, 300 μg/kg/min). Age-mat...

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Main Authors: Ana Arnalich-Montiel, María Carmen González, Emilio Delgado-Baeza, María Jesús Delgado-Martos, Luis Condezo-Hoyos, Antonia Martos-Rodríguez, Pilar Rodríguez-Rodríguez, Begoña Quintana-Villamandos
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/531087

Internet

http://dx.doi.org/10.1155/2014/531087

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