Fatty Acid Biosynthesis Inhibition Increases Reduction Potential in Neuronal Cells under Hypoxia

Recently, we have reported a novel neuronal specific pathway for adaptation to hypoxia through increased fatty acid (FA) biosynthesis (FAS) followed by esterification into lipids. However, the biological role of this pathway under hypoxia remains to be elucidated. In the presented study, we have t...

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Bibliographic Details
Main Authors: Stephen A Brose, Svetlana A Golovko, Mikhail Y Golovko
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Neuroscience
Subjects:
NAD
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00546/full