Shape dependent cytotoxicity of PLGA-PEG nanoparticles on human cells

Abstract We investigated the influence of nanoparticles’ shape on the physiological responses of cells, when they were fed with spherical and needle-shaped PLGA-PEG nanoparticles (the volume of the nanoparticles had been chosen as the fixed parameter). We found that both types of NPs entered cells v...

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Bibliographic Details
Main Authors: Bokai Zhang, Ping Sai Lung, Saisai Zhao, Zhiqin Chu, Wojciech Chrzanowski, Quan Li
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07588-9