Role of influenza A virus NP acetylation on viral growth and replication

Post-translational modifications of influenza A virus proteins can regulate virus replication, but the effect of nucleoprotein (NP) acetylation is not known. Here, Giese et al. identify four NP lysine residues that are acetylated in infected cells and study their role in polymerase activity and viri...

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Bibliographic Details
Main Authors: Sebastian Giese, Kevin Ciminski, Hardin Bolte, Étori Aguiar Moreira, Seema Lakdawala, Zehan Hu, Quinnlan David, Larissa Kolesnikova, Veronika Götz, Yongxu Zhao, Jörn Dengjel, Y. Eugene Chin, Ke Xu, Martin Schwemmle
Format: Article
Language:English
Published: Nature Publishing Group 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01112-3