Long Non-coding RNA MIR570MG Causes Regorafenib Resistance in Colon Cancer by Repressing miR-145/SMAD3 Signaling

Long Non-coding RNA MIR570MG Causes Regorafenib Resistance in Colon Cancer by Repressing miR-145/SMAD3 Signaling

An increasing number of studies have shown that long non-coding RNA (lncRNA) dysregulation plays a fundamental role in the development of various cancers, including colon cancer. Nonetheless, the mechanisms of lncRNA in regorafenib-resistance remain unclear. Our research revealed the lncRNA MIR570MG...

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Bibliographic Details
Main Authors: Fang Wei, Mofei Wang, Zhen Li, Yong Wang, Yong Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Oncology
Subjects:
LncRNA MIR570MG
miR-145
SMAD3
TGFβ
metastatic colon cancer
regorafenib
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00291/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.00291/full

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