The Effects of Repetitive Use and Pathological Remodeling on Channelrhodopsin Function in Cardiomyocytes
Aim: Channelrhodopsins (ChRs) are a large family of light-gated ion channels with distinct properties, which is of great importance in the selection of a ChR variant for a given application. However, data to guide such selection for cardiac optogenetic applications are lacking. Therefore, we investi...
Main Authors: | Balázs Ördög, Alexander Teplenin, Tim De Coster, Cindy I. Bart, Sven O. Dekker, Juan Zhang, Dirk L. Ypey, Antoine A. F. de Vries, Daniël A. Pijnappels |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-08-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2021.710020/full |
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