Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation

Necrotizing enterocolitis (NEC) is one of the most lethal gastrointestinal emergencies in neonates needing precision treatment. Here the authors show that remote ischemic conditioning is a non-invasive therapeutic method that enhances blood flow in the intestine, reduces damage, and improves NEC out...

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Bibliographic Details
Main Authors: Yuhki Koike, Bo Li, Niloofar Ganji, Haitao Zhu, Hiromu Miyake, Yong Chen, Carol Lee, Maarten Janssen Lok, Carlos Zozaya, Ethan Lau, Dorothy Lee, Sinobol Chusilp, Zhen Zhang, Masaya Yamoto, Richard Y. Wu, Mikihiro Inoue, Keiichi Uchida, Masato Kusunoki, Paul Delgado-Olguin, Luc Mertens, Alan Daneman, Simon Eaton, Philip M. Sherman, Agostino Pierro
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18750-9