Machines vs. ensembles: effective MAPK signaling through heterogeneous sets of protein complexes.

Despite the importance of intracellular signaling networks, there is currently no consensus regarding the fundamental nature of the protein complexes such networks employ. One prominent view involves stable signaling machines with well-defined quaternary structures. The combinatorial complexity of s...

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Bibliographic Details
Main Authors: Ryan Suderman, Eric J Deeds
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3794900?pdf=render