Association between DNA mismatch repair gene polymorphisms and platinum-based chemotherapy toxicity in non-small cell lung cancer patients

Association between DNA mismatch repair gene polymorphisms and platinum-based chemotherapy toxicity in non-small cell lung cancer patients

Abstract Background Chemotherapy toxicity is a serious problem from which non-small cell lung cancer (NSCLC) patients suffer. The mismatch repair (MMR) system is associated with platinum-based chemotherapy toxicity in NSCLC patients. In this study, we aimed to investigate the relationship between ge...

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Bibliographic Details
Main Authors: Jun-Yan Liu, Chen-Yue Qian, Yuan-Feng Gao, Juan Chen, Hong-Hao Zhou, Ji-Ye Yin
Format: Article
Language:English
Published: BMC 2017-01-01
Series:Chinese Journal of Cancer
Subjects:
DNA mismatch repair
Lung cancer
Chemotherapy toxicity
Platinum
Online Access:http://link.springer.com/article/10.1186/s40880-016-0175-2

Internet

http://link.springer.com/article/10.1186/s40880-016-0175-2

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