Lineages of embryonic stem cells show non-Markovian state transitions

Summary: Pluripotent embryonic stem cells (ESCs) constitute the cell types of the adult vertebrate through a series of developmental state transitions. These states can be defined by expression levels of marker genes, such as Nanog and Sox2. In culture, ESCs reversibly transition between states. How...

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Bibliographic Details
Main Authors: Tee Udomlumleart, Sofia Hu, Salil Garg
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221008476