Stemness of the CT-2A Immunocompetent Mouse Brain Tumor Model: Characterization In Vitro

<p>Evidence has pointed to brain tumor stem cells (BTSC) as culprits behind human high-grade glioma (hHGG) resistance to standard therapy. Pre-clinical rodent models are the mainstay for testing of new therapeutic strategies. The typical model involves the intracranial injection of human gliom...

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Bibliographic Details
Main Author: Emanuela Binello, Zulekha A. Qadeer, Harini P. Kothari, Luni Emdad, Isabelle M. Germano
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:Journal of Cancer
Online Access:http://www.jcancer.org/v03p0166.htm