Rheumatic heart disease: molecules involved in valve tissue inflammation leading to the autoimmune process and anti - S. pyogenes vaccine

The major events leading to both rheumatic fever and rheumatic heart disease are reviewed. Several genes are involved in the development of rheumatic fever (RF) and rheumatic heart disease (RHD). The inflammatory process that results from S. pyogenes infection involves the activation of several mole...

Full description

Bibliographic Details
Main Authors: Luiza eGuilherme, Jorge eKalil
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00352/full