Rheumatic heart disease: molecules involved in valve tissue inflammation leading to the autoimmune process and anti - S. pyogenes vaccine
The major events leading to both rheumatic fever and rheumatic heart disease are reviewed. Several genes are involved in the development of rheumatic fever (RF) and rheumatic heart disease (RHD). The inflammatory process that results from S. pyogenes infection involves the activation of several mole...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-10-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00352/full |