Bupropion use and risk of open-angle glaucoma among enrollees in a large U.S. managed care network.

Tumor Necrosis Factor (TNF) mediates retinal ganglion cell death in glaucoma. Anti-TNF drugs are neuroprotective in an animal model of glaucoma. It is unclear whether medications with anti-TNF properties such as bupropion have an impact on the risk of developing open-angle glaucoma (OAG) in humans....

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Bibliographic Details
Main Authors: Joshua D Stein, Nidhi Talwar, Jae H Kang, Olivia I Okereke, Janey L Wiggs, Louis R Pasquale
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395241?pdf=render