Synthesis of New Imidazolidin-2,4-dione and 2-Thioxoimidazolidin-4-ones via C-Phenylglycine Derivatives

Hydantoins and their derivatives constitute a group of pharmaceutical compounds with anticonvulsant and antiarrhythmic properties, and are also used against diabetes. N-3 and C-5 substituted imidazolidines are examples of such products. As such, we have developed a synthesis of 2,4-dione and 2-thiox...

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Main Authors: José Alixandre de Sousa Luis, José Maria Barbosa Filho, Bruno Freitas Lira, Isac Almeida Medeiros, Liana Clébia Soares Lima de Morais, Alexsandro Fernandes dos Santos, Cledualdo Soares de Oliveira, Petrônio Filgueiras de Athayde-Filho
Format: Article
Language:English
Published: MDPI AG 2009-12-01
Series:Molecules
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Online Access:http://www.mdpi.com/1420-3049/15/1/128/