A mitofusin-dependent docking ring complex triggers mitochondrial fusion in vitro

Fusion of mitochondrial outer membranes is crucial for proper organelle function and involves large GTPases called mitofusins. The discrete steps that allow mitochondria to attach to one another and merge their outer membranes are unknown. By combining an in vitro mitochondrial fusion assay with ele...

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Bibliographic Details
Main Authors: Tobias Brandt, Laetitia Cavellini, Werner Kühlbrandt, Mickaël M Cohen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/14618