Natural Dietary Supplementation of Curcumin Protects Mice Brains against Ethanol-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment via Nrf2/TLR4/RAGE Signaling

Natural Dietary Supplementation of Curcumin Protects Mice Brains against Ethanol-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment via Nrf2/TLR4/RAGE Signaling

The aim of the current study was to explore the underlying neuroprotective mechanisms of curcumin (50 mg/kg, for six weeks) against ethanol (5 mg/kg i.p., for six weeks) induced oxidative stress and inflammation-mediated cognitive dysfunction in mice. According to our findings, ethanol triggered rea...

Full description

Bibliographic Details
Main Authors: Muhammad Ikram, Kamran Saeed, Amjad Khan, Tahir Muhammad, Muhammad Sohail Khan, Min Gi Jo, Shafiq Ur Rehman, Myeong Ok Kim
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Nutrients
Subjects:
neurodegenerative diseases
oxidative stress
neuroinflammation
apoptosis
synaptic dysfunction
Online Access:https://www.mdpi.com/2072-6643/11/5/1082

Internet

https://www.mdpi.com/2072-6643/11/5/1082

Similar Items