Transcriptional and epigenetic regulation of KIF14 overexpression in ovarian cancer.

KIF14 (kinesin family member 14) is a mitotic kinesin and an important oncogene in several cancers. Tumor KIF14 expression levels are independently predictive of poor outcome, and in cancer cells KIF14 can modulate metastatic behavior by maintaining appropriate levels of cell adhesion and migration...

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Bibliographic Details
Main Authors: Brigitte L Thériault, Halesha D Basavarajappa, Harvey Lim, Sanja Pajovic, Brenda L Gallie, Timothy W Corson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3953446?pdf=render