The INO80 Complex Removes H2A.Z to Promote Presynaptic Filament Formation during Homologous Recombination

The INO80 Complex Removes H2A.Z to Promote Presynaptic Filament Formation during Homologous Recombination

The INO80 complex (INO80-C) is an evolutionarily conserved nucleosome remodeler that acts in transcription, replication, and genome stability. It is required for resistance against genotoxic agents and is involved in the repair of DNA double-strand breaks (DSBs) by homologous recombination (HR). How...

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Bibliographic Details
Main Authors: Claudio A. Lademann, Jörg Renkawitz, Boris Pfander, Stefan Jentsch
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Cell Reports
Subjects:
homologous recombination
double-strand breaks
chromatin
nucleosome remodeling
genome stability
INO80-C
H2A.Z
Rad51 filament formation
DNA end resection
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717305454

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http://www.sciencedirect.com/science/article/pii/S2211124717305454

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