Osthole Ameliorates Estrogen Deficiency-Induced Cognitive Impairment in Female Mice

Osthole Ameliorates Estrogen Deficiency-Induced Cognitive Impairment in Female Mice

Loss of endogenous estrogen and dysregulation of the estrogen receptor signaling pathways are associated with an increase in risk for cognitive deficit and depression in women after menopause. Estrogen therapy for menopause increases the risk of breast and ovarian cancers, and stroke. Therefore, it...

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Bibliographic Details
Main Authors: Frank Adu-Nti, Xu Gao, Jia-Min Wu, Jing Li, Javed Iqbal, Riaz Ahmad, Xin-Ming Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
estradiol
ovariectomy
depression-like behaviors
cognitive deficit
hippocampus
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.641909/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.641909/full

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