Evolutionary Conservation of Bacterial Essential Metabolic Genes across All Bacterial Culture Media.

One of the basic postulates of molecular evolution is that functionally important genes should evolve slower than genes of lesser significance. Essential genes, whose knockout leads to a lethal phenotype are considered of high functional importance, yet whether they are truly more conserved than non...

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Bibliographic Details
Main Authors: Oren Ish-Am, David M Kristensen, Eytan Ruppin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4403854?pdf=render