Decreased expression of circ_0020397 in intracranial aneurysms may be contributing to decreased vascular smooth muscle cell proliferation via increased expression of miR-138 and subsequent decreased KDR expression

Decreased expression of circ_0020397 in intracranial aneurysms may be contributing to decreased vascular smooth muscle cell proliferation via increased expression of miR-138 and subsequent decreased KDR expression

Dysfunction of vascular smooth muscle cells (VSMCs) mediates intracranial aneurysm (IA). KDR is reported to alleviate IA progression via promoting VSMC proliferation, while the upstream regulators are still unclear. Arterial wall tissues at the aneurysm site from 12 patients were obtained. The real-...

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Bibliographic Details
Main Authors: Yushe Wang, Yong Wang, Yu Li, Bin Wang, Zhuang Miao, Xianzhi Liu, Yuanyuan Ma
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Cell Adhesion & Migration
Subjects:
intracranial aneurysm
circ_0020397
mir-138
kdr
cell proliferation
Online Access:http://dx.doi.org/10.1080/19336918.2019.1619432

Internet

http://dx.doi.org/10.1080/19336918.2019.1619432

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