Histone H3E73Q and H4E53A mutations cause recombinogenic DNA damage

The stability and function of eukaryotic genomes is closely linked to histones and to chromatin structure. The state of the chromatin not only affects the probability of DNA to undergo damage but also DNA repair. DNA damage can result in genetic alterations and subsequent development of cancer and o...

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Bibliographic Details
Main Authors: Pedro Ortega, Desiré García-Pichardo, Marta San Martin-Alonso, Ana G. Rondón, Belén Gómez-González, Andrés Aguilera
Format: Article
Language:English
Published: Shared Science Publishers OG 2020-04-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/2020a-ortega-microbial-cell/