Derivation of human embryonic stem cell from spinal muscular atrophy patient

We established a human embryonic stem cell (hESC) line chHES-427 from the abnormal embryo carrying homozygous deletion of exon 7 of survival motor neuron gene (SMN). This cell line maintained a normal karyotype 46, XX during long-term culture. Further characteristic analysis suggested that the cells...

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Bibliographic Details
Main Authors: Pingyuan Xie, Hao Zhou, Xiaoying Zhou, Xiaomeng Zhao, Juan Du, Guangxiu Lu, Ge Lin, Qi Ouyang
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S187350611500210X