Fisetin Prevents Acetaminophen-Induced Liver Injury by Promoting Autophagy

Fisetin Prevents Acetaminophen-Induced Liver Injury by Promoting Autophagy

Acetaminophen (APAP) overdose is a leading cause of drug-induced acute liver failure in clinical and hospital settings. Fisetin (FST) is a phenolic compound derived from natural products such as fruit and vegetables. Our research investigated the protective mechanisms of FST in APAP-induced hepatic...

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Bibliographic Details
Main Authors: Jiaqi Zhang, Licong Zhao, Cheng Hu, Tao Wang, Juan Lu, Chenqu Wu, Long Chen, Mingming Jin, Hao Hu, Guang Ji, Qin Cao, Yuanye Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Pharmacology
Subjects:
acetaminophen
liver injury
fisetin
autophagy
ATG5
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00162/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00162/full

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