Striatal intrinsic reinforcement signals during recognition memory: relationship to response bias and dysregulation in schizophrenia

Ventral striatum (VS) is a critical brain region for reinforcement learning and motivation, and VS hypofunction is implicated in psychiatric disorders including schizophrenia. Providing rewards or performance feedback has been shown to activate VS. Intrinisically motivated subjects performing chall...

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Bibliographic Details
Main Authors: Daniel H Wolf, Raphael T Gerraty, Theodore D. Satterthwaite, James eLoughead, Timothy eCampellone, Mark A Elliott, Bruce I Turetsky, Ruben C Gur, Raquel E Gur
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2011.00081/full