Lipoxin A4 and its analog suppress inflammation by modulating HMGB1 translocation and expression in psoriasis

Lipoxin A4 and its analog suppress inflammation by modulating HMGB1 translocation and expression in psoriasis

Abstract Psoriasis is a chronic inflammatory skin disease that affects 2–3% of the global population, and there is still no known possibility of a cure. Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties. BML-111...

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Bibliographic Details
Main Authors: Xinxin Liu, Xin Wang, Xiaoru Duan, Devesh Poorun, Juntao Xu, Song Zhang, Lu Gan, Mengwen He, Ke Zhu, Zhangyin Ming, Feng Hu, Hongxiang Chen
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07485-1

Internet

https://doi.org/10.1038/s41598-017-07485-1

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