Re-evaluating the relationship between missing heritability and the microbiome

Abstract Human genome-wide association studies (GWASs) have recurrently estimated lower heritability estimates than familial studies. Many explanations have been suggested to explain these lower estimates, including that a substantial proportion of genetic variation and gene-by-environment interacti...

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Bibliographic Details
Main Authors: Gavin M. Douglas, Joseph P. Bielawski, Morgan G. I. Langille
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Microbiome
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40168-020-00839-4