Effect of moxibustion on mTOR-mediated autophagy in rotenone-induced Parkinson's disease model rats

Effect of moxibustion on mTOR-mediated autophagy in rotenone-induced Parkinson's disease model rats

Defects in autophagy-mediated clearance of α-synuclein may be one of the key factors leading to progressive loss of dopaminergic neurons in the substantia nigra. Moxibustion therapy for Parkinson's disease has been shown to have a positive effect, but the underlying mechanism remains unknown. B...

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Bibliographic Details
Main Authors: Shu-ju Wang, Qi Wang, Jun Ma, Pei-hao Yu, Zhong-ming Wang, Bin Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; neurodegeneration; Parkinson′s disease; acupuncture; moxibustion; rotenone; alpha-synuclein; autophagy; phosphorylated mammalian target of rapamycin kinase; phosphorylated ribosomal protein S6 kinase; light chain 3-II; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=1;spage=112;epage=118;aulast=Wang

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=1;spage=112;epage=118;aulast=Wang

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