Platform Randomised trial of INterventions against COVID-19 In older peoPLE (PRINCIPLE): protocol for a randomised, controlled, open-label, adaptive platform, trial of community treatment of COVID-19 syndromic illness in people at higher risk

Introduction There is an urgent need to idenfy treatments for COVID-19 that reduce illness duration and hospital admission in those at higher risk of a longer illness course and complications.Methods and analysis The Platform Randomised trial of INterventions against COVID-19 In older peoPLE trial i...

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Main Authors: Jienchi Dorward, Susan Hopkins, Gail Hayward, Ly-Mee Yu, Oliver van Hecke, Julie Allen, Emma Ogburn, Heather Rutter, Oghenekome Gbinigie, Sharon Tonner, Aleksandra Borek, Philip H Evans, Martin Llewelyn, Benjamin R Saville, Nicholas Berry, Hannah Swayze, David Judge, Jenna Grabey, Nicholas P B Thomas, Monique I Andersson, Mahendra Patel
Format: Article
Language:English
Published: BMJ Publishing Group 2021-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/6/e046799.full