An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection.

An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection.

Salmonella Typhimurium (S.Tm) is a common cause of self-limiting diarrhea. The mucosal inflammation is thought to arise from a standoff between the pathogen's virulence factors and the host's mucosal innate immune defenses, particularly the mucosal NAIP/NLRC4 inflammasome. However, it had...

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Bibliographic Details
Main Authors: Anna A Müller, Tamas Dolowschiak, Mikael E Sellin, Boas Felmy, Carolin Verbree, Sandra Gadient, Alexander J Westermann, Jörg Vogel, Salome LeibundGut-Landmann, Wolf-Dietrich Hardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4920399?pdf=render

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http://europepmc.org/articles/PMC4920399?pdf=render

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