Serial Block-Face Scanning Electron Microscopy to Reconstruct Three-Dimensional Tissue Nanostructure

<p>Three-dimensional (3D) structural information on many length scales is of central importance in biological research. Excellent methods exist to obtain structures of molecules at atomic, organelles at electron microscopic, and tissue at light-microscopic resolution. A gap exists, however, wh...

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Bibliographic Details
Main Authors: Denk Winfried, Horstmann Heinz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-01-01
Series:PLoS Biology
Subjects:
Online Access:http://dx.doi.org/10.1371/journal.pbio.0020329