Modulating effect of Coronarin D in 5-fluorouracil resistance human oral cancer cell lines induced apoptosis and cell cycle arrest through JNK1/2 signaling pathway

Coronarin D (CD) is one of the main components of Hedychium coronarium rhizome, which has therapeutic potential by reducing cell proliferation in cancer cells. However, the mechanism of CD to 5-fluorouracil (5FU) oral cancer cell remain unclearly. This study discusses the CD to 5FU chemoresistance o...

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Bibliographic Details
Main Authors: Ming-Yu Hsieh, Ming-Ju Hsieh, Yu-Sheng Lo, Chia-Chieh Lin, Yi-Ching Chuang, Mu-Kuan Chen, Ming-Chih Chou
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
JNK
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220305102