Apelin promotes blood and lymph vessel formation and the growth of melanoma lung metastasis

Apelin promotes blood and lymph vessel formation and the growth of melanoma lung metastasis

Abstract Apelin, a ligand of the APJ receptor, is overexpressed in several human cancers and plays an important role in tumor angiogenesis and growth in various experimental systems. We investigated the role of apelin signaling in the malignant behavior of cutaneous melanoma. Murine B16 and human A3...

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Main Authors: Judit Berta, Szilvia Török, Júlia Tárnoki-Zách, Orsolya Drozdovszky, József Tóvári, Sándor Paku, Ildikó Kovács, András Czirók, Bernard Masri, Zsolt Megyesfalvi, Henriett Oskolás, Johan Malm, Christian Ingvar, György Markó-Varga, Balázs Döme, Viktória László
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85162-0

Internet

https://doi.org/10.1038/s41598-021-85162-0

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