Optimization of the Transwell<sup>®</sup> System for Assessing the Dissolution Behavior of Orally Inhaled Drug Products through In Vitro and In Silico Approaches

Optimization of the Transwell<sup>®</sup> System for Assessing the Dissolution Behavior of Orally Inhaled Drug Products through In Vitro and In Silico Approaches

The aim of this study was to further evaluate and optimize the Transwell<sup>®</sup> system for assessing the dissolution behavior of orally inhaled drug products (OIDPs), using fluticasone propionate as a model drug. Sample preparation involved the collection of a relevant inhalable dos...

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Bibliographic Details
Main Authors: Elham Amini, Abhinav Kurumaddali, Sharvari Bhagwat, Simon M. Berger, Günther Hochhaus
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceutics
Subjects:
orally inhaled drug products
dissolution
Transwell<sup>®</sup>
sample preparation
anatomical mouth–throat model
mathematical modelling
Online Access:https://www.mdpi.com/1999-4923/13/8/1109

Internet

https://www.mdpi.com/1999-4923/13/8/1109

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