Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus

Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus

Abstract Background Periventricular extracellular oedema, myelin damage, inflammation, and glial reactions are common neuropathological events that occur in the brain in congenital hydrocephalus. The periventricular white matter is the most affected region. The present study aimed to identify altere...

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Bibliographic Details
Main Authors: Betsaida Ojeda-Pérez, José A. Campos-Sandoval, María García-Bonilla, Casimiro Cárdenas-García, Patricia Páez-González, Antonio J. Jiménez
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Fluids and Barriers of the CNS
Subjects:
Biomarkers
Hereditary hydrocephalus
Energy dispersive X-ray spectroscopy (EDS)
Lipids
Ultrahigh-performance liquid chromatography-high-resolution mass spectrometry (UHPLC–HRMS)
Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI)
Online Access:https://doi.org/10.1186/s12987-021-00263-2

Internet

https://doi.org/10.1186/s12987-021-00263-2

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