Comparing proteomics and RISC immunoprecipitations to identify targets of Epstein-Barr viral miRNAs.

Epstein-Barr virus is a gamma-herpes virus that is causally associated with several lymphomas and carcinomas. This virus encodes at least 25 pre-miRNAs, which are expressed in infected cells to yield more than 50 detected mature miRNAs. miRNAs are small, non-coding RNAs that inhibit gene expression...

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Bibliographic Details
Main Authors: Malika Kuzembayeva, Ya-Fang Chiu, Bill Sugden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3472983?pdf=render