Monocyte Chemoattractant Protein 1 Promotes VEGF-A Expression in OSCC by Activating ILK and MEK1/2 Signaling and Downregulating miR-29c

Monocyte Chemoattractant Protein 1 Promotes VEGF-A Expression in OSCC by Activating ILK and MEK1/2 Signaling and Downregulating miR-29c

Oral squamous cell carcinoma (OSCC) is an aggressive tumor that has a poor prognosis, with high levels of local invasion and lymph node metastasis. Vascular endothelial growth factor A (VEGF-A) plays essential roles in OSCC tumor angiogenesis and metastasis. Monocyte chemoattractant protein-1 (MCP-1...

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Bibliographic Details
Main Authors: Ming-Yu Lien, An-Chen Chang, Hsiao-Chi Tsai, Ming-Hsui Tsai, Chun-Hung Hua, Shih-Ping Cheng, Shih-Wei Wang, Chih-Hsin Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
monocyte chemoattractant protein-1
vascular endothelial growth factor A
miR-29c
oral squamous cell carcinoma
angiogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.592415/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.592415/full

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