Personalized genome structure via single gamete sequencing
Abstract Genetic maps have been fundamental to building our understanding of disease genetics and evolutionary processes. The gametes of an individual contain all of the information required to perform a de novo chromosome-scale assembly of an individual’s genome, which historically has been perform...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-04-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-021-02327-w |