Gene co-expression networks shed light into diseases of brain iron accumulation

Gene co-expression networks shed light into diseases of brain iron accumulation

Aberrant brain iron deposition is observed in both common and rare neurodegenerative disorders, including those categorized as Neurodegeneration with Brain Iron Accumulation (NBIA), which are characterized by focal iron accumulation in the basal ganglia. Two NBIA genes are directly involved in iron...

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Bibliographic Details
Main Authors: Conceição Bettencourt, Paola Forabosco, Sarah Wiethoff, Moones Heidari, Daniel M. Johnstone, Juan A. Botía, Joanna F. Collingwood, John Hardy, Elizabeth A. Milward, Mina Ryten, Henry Houlden
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Neurobiology of Disease
Subjects:
Human brain
Whole-transcriptome analysis
WGCNA
NBIA
Iron metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115301066

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http://www.sciencedirect.com/science/article/pii/S0969996115301066

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