Direct comparison of [11C] choline and [18F] FET PET to detect glioma infiltration: a diagnostic accuracy study in eight patients

Abstract Background Positron emission tomography (PET) is increasingly used to guide local treatment in glioma. The purpose of this study was a direct comparison of two potential tracers for detecting glioma infiltration, O-(2-[18F]-fluoroethyl)-l-tyrosine ([18F] FET) and [11C] choline. Methods Eigh...

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Main Authors: Niels Verburg, Thomas Koopman, Maqsood Yaqub, Otto S. Hoekstra, Adriaan A. Lammertsma, Lothar A. Schwarte, Frederik Barkhof, Petra J. W. Pouwels, Jan J. Heimans, Jaap C. Reijneveld, Annemieke J. M. Rozemuller, William P. Vandertop, Pieter Wesseling, Ronald Boellaard, Philip C. de Witt Hamer
Format: Article
Language:English
Published: SpringerOpen 2019-06-01
Series:EJNMMI Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13550-019-0523-8