Total Cellular ATP Production Changes With Primary Substrate in MCF7 Breast Cancer Cells

Total Cellular ATP Production Changes With Primary Substrate in MCF7 Breast Cancer Cells

Cancer growth is predicted to require substantial rates of substrate catabolism and ATP turnover to drive unrestricted biosynthesis and cell growth. While substrate limitation can dramatically alter cell behavior, the effects of substrate limitation on total cellular ATP production rate is poorly un...

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Bibliographic Details
Main Authors: Maggie C. Louie, Justin Ton, Maurice L. Brady, Diem T. Le, Jordon N. Mar, Chad A. Lerner, Akos A. Gerencser, Shona A. Mookerjee
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
glycolysis
oxidative phosphorylation
Crabtree
ATP supply flexibility
bioenergetic capacity
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.01703/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.01703/full

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