Persistent Hyperactivity of Hippocampal Dentate Interneurons after a Silent Period in the Rat Pilocarpine Model of Epilepsy

Persistent Hyperactivity of Hippocampal Dentate Interneurons after a Silent Period in the Rat Pilocarpine Model of Epilepsy

Profile of GABAergic interneuron activity after pilocarpine-induced status epilepticus (SE) was examined in the rat hippocampal dentate gyrus by analyzing immediate early gene expression and recording spontaneous firing at near resting membrane potential.SE for exact 2 hours or more than 2 hours was...

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Bibliographic Details
Main Authors: Xiaochen eWang, Xinyu eSong, Lin eWu, J Victor Nadler, Ren-Zhi eZhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Neuropeptides
c-fos
plasticity
GABAergic
parvalbumin
Immediate early genes
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00094/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00094/full

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