The novel rexinoid MSU-42011 is effective for the treatment of preclinical Kras-driven lung cancer

Abstract Effective drugs are needed for lung cancer, as this disease remains the leading cause of cancer-related deaths. Rexinoids are promising drug candidates for cancer therapy because of their ability to modulate genes involved in inflammation, cell proliferation or differentiation, and apoptosi...

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Bibliographic Details
Main Authors: Jessica A. Moerland, Di Zhang, Lyndsey A. Reich, Sarah Carapellucci, Beth Lockwood, Ana S. Leal, Teresa Krieger-Burke, Bilal Aleiwi, Edmund Ellsworth, Karen T. Liby
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79260-8