Single-Cell RNA-seq Reveals Profound Alterations in Mechanosensitive Dorsal Root Ganglion Neurons with Vitamin E Deficiency

Single-Cell RNA-seq Reveals Profound Alterations in Mechanosensitive Dorsal Root Ganglion Neurons with Vitamin E Deficiency

Summary: Ninety percent of Americans consume less than the estimated average requirements of dietary vitamin E (vitE). Severe vitE deficiency due to genetic mutations in the tocopherol transfer protein (TTPA) in humans results in ataxia with vitE deficiency (AVED), with proprioceptive deficits and s...

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Bibliographic Details
Main Authors: Carrie J. Finno, Janel Peterson, Mincheol Kang, Seojin Park, Matthew H. Bordbari, Blythe Durbin-Johnson, Matthew Settles, Maria C. Perez-Flores, Jeong H. Lee, Ebenezer N. Yamoah
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219304456

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http://www.sciencedirect.com/science/article/pii/S2589004219304456

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